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refrigeração (2-8°C): 24 horas. •pode ter sua ação diminuída por: alimento com alto teor de cálcio (leite e laticínios); antiácido; droga contendo ferro, cálcio ou magnésio. Clodronate (clodronate disodium, Bonefos®) is a non-nitrogen-containing bisphosphonate that inhibits osteoclast activity, and thereby inhibits bone resorption. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). Clodronate is a medicine used to treat a high level of calcium in the blood caused by changes in the body that happen with cancer. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Special pediatric considerations are noted when applicable, otherwise adult provisions apply. Site designed by Pharma Professional Services and developed by Hasan Computing Systems. It is also used to treat a high level of calcium in the blood that may occur with some cancers. Clodronate is not metabolised and most of the dose appears in the urine within a few days. Brand Name: Clophosome ® Active: clodronate disodium. Osteolytic lesions, hypercalcaemia and bone pain associated with skeletal metastases in patients with breast cancer or multiple myeloma. Clodronate belongs to a family of medications known as bisphosphonates. Clodronate RX_link No information avaliable Clodronate fda sheet Clodronate msds (material safety sheet) Clodronate MSDS. Clodronate Synthesis Reference No information avaliable - 6 ampoules For SODIUM CLODRONATE. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. DA = Draining area of lymph node. It is used to treat high calcium levels in patients with cancer. It is used to treat hypercalcemia (high blood calcium) for people who have cancer. It is used to stop bone loss. Macrophage Depletion Kit (Mannosylated) O MedicinaNET é o maior portal médico em português. Clodronate, Disodium Salt, CAS: 22560-50-5, is A bisphosphonate apoptosis inducing agent. Back to top. Company: Berlex, Inc. Volume: 500 mL. Kanis JA(1), McCloskey EV. inibe a reabsorção óssea que leva a aumento do cálcio no sangue. hipercalcemia devido a tumores malignos ou metástases ósseas; osteólise (dissolução do osso) devido a metástase de tumores sólidos (câncer de mama, próstata ou tireoide) ou devido a neoplasia sanguínea (mieloma múltiplo). Previous Drug Generic - Next Drug Generic. Clodronate also treats the weakening in the bones when cancer has spread to the bones from another part of the body. What is this drug used for? inflamação aguda do estômago ou intestino; diminuição da função renal. By mouth. dados não disponibilizados; não amamentar. Lipid composition: phosphatidylcholine and cholesterol. Parecoxib is predicted to increase the risk of renal impairment when given with clodronate. Description and Brand Names. Parecoxib. Cápsula 400 mg: Bonefós Uso injetável. Clodronate also treats the weakening in the bones when cancer has spread to the bones from another part of the body. Dermatológico: hipersensibilidade na pele. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Sodium clodronate is a bisphosphonate and is prescribed for problems which affect bones. Clodronate. It is also called Bonefos, Clasteon, and Loron 520 Injetável (solução) 1500 mg/25 mL: Bonefós Injetável (solução) 300 mg/5 mL: Bonefós O que é Mayo Clinic does not endorse companies or products. Suggested Pages. Clodronate. BM = Bone marrow. Drug information provided by: IBM Micromedex. Manufacturer advises avoid. Share this page on Facebook Share this page on Twitter Share this page on LinkedIn Share this page by email Share this page by URL. Sodium clodronate (as tetrahydrate). Back to top. CAS: 22560-50-5, 7 mg/mL . All rights reserved. Adverse reactions include renal insufficiency and hypocalcaemia. In other countries is prescribed as a bone resorption inhibitor and antihypercalcemic agent. Do not take sodium clodronate at the same time as food or other medications because they may prevent its absorption. Drug information provided by: IBM Micromedex. Purified talc, calcium stearate, anhydrous colloidal silica, lactose, gelatin, purified water, iron oxide red, iron oxide yellow, Tekprint SW-9008 black ink and titanium dioxide. Disclaimer. Bonefos Bayer, United Kingdom; Bayer, Tunisia; Er-Kim, Turkey; IFET, Greece Treatment for: Breast Cancer, Adjuvant. Tribo™ Human IFN gamma ELISA Kit; Tribo™ Human β2-microglobulin ELISA Kit; Human TNFꭤ ELISA kit; 1 step and 1hr; Fast Human TGF-β1 ELISA 1. •com 1 copo cheio de água, em jejum, pelo menos 30 minutos antes do café da manhã. MedicinaNET - Todos os direitos reservados. The bad news is that clodronate is not directly available in the United States. 12 Equine Key Opinions Leaders in English Performance, Western Performance, Take this medication 1 to 2 hours (depending on your brand) before or 1 to 2 hours after taking any products that contain aluminum, calcium, iron, magnesium, or zinc. Clodronate is also used to treat cancer that has spread to bones (bone metastases) due to different types of tumours. Manufacturers of Clodronate in Pakistan. Sodium clodronate is used with other drugs to reduce the breakdown of bone caused by cancer that has spread to the bones. BV = Blood vessels (circulation) BR = Brain. Copyright © 2021 IBM Watson Health. 1600 mg por dia, em dose única. Clodronate is predicted to decrease the effects of parathyroid hormone. Generic names: clodronate disodium, clodronic acid disodium tetrahydrate; Brand names: Clasteon, Clastoban, Climaclod, Clodeosten, Clodran, Clodron, Clody, Difosfonal, Disdual, Lodronat, Loron, Lytos, Mebonat, Moticlod, Niklod, Ossiten, Ostac, Osteonorm, Osteostab, Sindronat; References ↑ Brand Names: Canada. Permanecemos com suporte aos nossos inscritos através do e-mail info@medicinanet.com.br. Bulk solution: phosphate buffered saline (20mM sodium phosphate, 09wt% NaCl), pH 7.0-7.5 Popular Products. Clodronate. Clodronato dissódico (solução) 1500 mg/25 mL – Infusão intravenosa. For Adult. classificação não disponibilizada; não usar. This medicine is available only with your doctor's prescription. All products: If you have an allergy to clodronate … Who? Inicial temperatura ambiente (15 - 25°C): 24 horas. CLODRONATO ABC Active Ingredient Clodronate 100 mg/3.3 ml injectable solution - 6 ampoules 100 mg/3.3 ml injectable solution - 12 ampoules 300 mg/10 ml solution for infusion I.V. LEGENDS: AL = Alveoli in lung. Share this page. MF: CH2Cl2O6P2Na2, MW: 288.86. EY = Eye. Reúne recursos indispensáveis e conteúdos de ponta contextualizados à realidade brasileira, sendo a melhor ferramenta de consulta para tomada de decisões rápidas e eficazes. Você está em: •interromper o tratamento se ocorrer comprometimento da função dos rins. Clodronate, Disodium Salt - CAS 22560-50-5 - Calbiochem 1 Product Result | Match Criteria: Product Name (claw-DROE-nate) is a drug that is used to treat cancer which has spread into the bones (bone metastases). It is a capsule that you take by mouth. Clodronate molecules are encapsulated in small MLV liposomes for superior activity, physical and chemical stability, and convenience of use and handling. Estabilidade após diluição com Cloreto de Sódio 0,9% temperatura ambiente (15 - 25°C): eliminação de proteínas pela urina; insuficiência renal aguda após administração intravenosa. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. geniturinário: eliminação de proteínas pela urina; insuficiência renal aguda após administração intravenosa. A dose máxima diária é de 3200 mg. A duração do tratamento é, em geral, de 6 meses. •doses em termos de Clodronato dissódico. About Us. Name of the medicine. Perspectives from an Equine Expert Panel on Clodronate Use in Horses. Hematológico: diminuição do cálcio no sangue. GU = Gut (intestines) Developer and worldwide provider of clodronate liposomes: Delivery on demand + Worldwide shipping & Easy Online Ordering 24/7 - Please Contact Us Clodronate binds to calcium and inhibits osteoclastic bone resorption and hydroxyapatite crystal formation and dissolution, resulting in a reduction of bone turnover. Descriptions. This content does not have an English version. Diluente: Cloreto de Sódio 0,9%. Each capsule contains the equivalent of … Background. Estabilidade após diluição com Cloreto de Sódio 0,9% temperatura ambiente (15 - 25°C): 6 horas. Cited in 1 publications Clodronato dissódico (solução) 300 mg/5 mL – Infusão intravenosa. Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Clodronic Acid (Oral Route, Injection Route), FREE book offer – Mayo Clinic Health Letter, New Year Special -  40% off – Mayo Clinic Diet Online. Brand names and generic names are differentiated by the use of capital initials for the former.. See also the list of the top 100 bestselling branded drugs, ranked by sales. Bonefos (clodronate) is a non-amino bisphosphonate intended to reduce the occurrence of bone metastases in the post-surgical (adjuvant) treatment of breast cancer patients. Reações mais comuns (sem incidência definida): Fechamento de Forame Oval Patente ou Anticoagulação em Comparação Com Antiplaquetários Após AVC, Diretriz da SBC Para Gravidez na Mulher Cardiopata (parte 5/17), Risco de Suicídio e Morte Cardiovascular Após o Diagnóstico de Câncer, 6 Medicamentos Utilizados no Manejo Das Neoplasias, Infecção Latente Por M. Tuberculosis e Atualização Terapêutica - Dr. Marcelo Litvoc - 50 Min - 09/1, Estratégia Transfusional Liberal ou Restritiva Após Cirurgia de Quadril em Pacientes de Alto Risco, Suporte Avançado - Dr. Ricardo Casalino Sanches de Moraes - 52 Min - 11/10, 3.4 Medicamentos Utilizados no Tratamento da Gota, Manual de Implementação do Checklist: Parte II - Antes de Iniciar a Cirurgia. You might have it as a treatment for a number of cancers that affect the bones such as myeloma and secondary breast cancer. medicamentos C. setTimeout("$('adwords').hide();", 10000); Both types of Clophsome ® are offered in the standard suspension form fo rthe convenience of use, the high potency form fo rdosing of high cotent with limited small volume and the lyophilized forms for the long shelf-life. Cancer. Sodium clodronate (Bonefos, Clasteon, Loron) Sodium clodronate is a type of bisphosphonate. Many drugs have more than one name and, therefore, the same drug may be listed more than once. Excipients Capsules. Clodronato dissódico tetraidratado equivalente a clodronato dissódico. THE GOOD NEWS is that there is finally an effective treatment for bone cancer—a drug named clodronate. Author information: (1)World Health Organization Collaborating Centre for Metabolic Bone Diseases, Department of Human Metabolism and Clinical Biochemistry, University of Sheffield Medical School, United Kingdom. Em função da pandemia do Coronavírus informamos que não estaremos prestando atendimento telefônico temporariamente. Clodronate has been extensively used in patients with advanced breast cancer, and is generally well tolerated. This content does not have an Arabic version. Portions of this document last updated: Feb. 01, 2020. setTimeout("$('adwordstopo').hide();", 10000); Injetável (solução) 1500 mg/25 mL: Bonefós. This multi-page article lists pharmaceutical drugs alphabetically by name. Clodronate works by reducing the breakdown of bone.This medication may be available under multiple brand names and/or in several different forms. Brand name: Bonefos. Bonefos [DSC]; Clasteon. 1997 Oct 15;80(8 Suppl):1691-5. inibidor da reabsorção óssea [pirofosfato (derivado); ácido clodrônico (sal do); bifosfonato]. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for SODIUM CLODRONATE. Severity of interaction: Moderate Evidence for interaction: Study. This site complies with the HONcode standard for trustworthy health information: verify here. Few diseases are as dehumanizing and as damaging to a … It is also used to treat the increased amount of calcium in the blood (hypercalcemia) that may occur with some kinds of cancer. Clodronate is a medicine used to treat a high level of calcium in the blood caused by changes in the body that happen with cancer. Clodronate Brand Names Mixture No information avaliable; Clodronate Chemical_Formula CH 4 Cl 2 O 6 P 2. Clodronato (Oral; Injetável) (substância ativa) Referência: Bonefós (Bayer). You may have sodium clodronate for 1 of the following reasons: to treat high blood calcium (hypercalcaemia) Clodronate sodium, also called clodronate disodium, is the disodium salt of a nitrogen-free bisphosphonate analog of naturally occurring pyrophosphate. Weight: 02 kg: Quantity: 5 ml (5ml Clodronate Liposomes), 10 ml (10ml Clodronate Liposomes), 15 ml (15ml Clodronate Liposomes), 20ml (20ml Clodronate Liposomes), 25 ml (25ml Clodronate Liposomes), 30 ml (30ml Clodronate Liposomes), 40 ml (40ml Clodronate Liposomes), 50 ml (50ml Clodronate Liposomes), 60 ml (60ml Clodronate Liposomes), 70 ml (70ml Clodronate Liposomes), 80 ml (80ml Clodronate … •evitar deitar por pelo menos 30 minutos. Estabilidade após diluição com Cloreto de Sódio 0,9% ou Glicose 5%. What do I need to tell my doctor BEFORE I take this drug? Clodronate DRUG NAME: Clodronate SYNONYM(S): Clodronate disodium, clodronic acid, Cl 2MDP, dichloromethylene bisphosphonate, disodium clodronate, sodium clodronate COMMON TRADE NAME(S): CLASTEON®, BONEFOS ; OSTAC CLASSIFICATION: Bone metabolism regulator. • doses em termos de Clodronato dissódico. Brands / Trade Names of Clodronate. Volume: 500 mL. All rights reserved. Patients must be adequately hydrated before treatment and renal function must be monitored. Diluente: Cloreto de Sódio 0,9% ou Glicose 5%. Clodronic acid is approved for human use in Canada and Australia, the United Kingdom, where it is marketed as Bonefos, Loron, Clodron and in Italy as Clasteon, Difosfonal, Osteostab and several generics. Generic name: clodronate. Advertising revenue supports our not-for-profit mission. Read More. •realizar periodicamente exames de sangue e da função do fígado. Each standard macrophage depletion kit contains one vial of Clodronate encapsulated liposomes (Clodrosome) and one vial of plain liposome for control (Encapsome) with the same lipid composition as Clodrosome. The terminal elimination half-life may exceed a year as clodronate bound to bone is slowly released. Genérico: não clodronato dissódico tetraidratado equivalente a clodronato dissódico Uso oral. 1.6 g daily in 1–2 divided doses, then increased if necessary up to 3.2 g daily in 2 divided doses. In several different forms 1.6 g daily in 2 divided doses, then increased If necessary to. As myeloma and secondary breast cancer, and is generally well tolerated this multi-page lists. Take sodium clodronate leva a aumento do cálcio No sangue by cancer that has spread to the (! End User 's use only and may not be sold, redistributed or otherwise for. Exames de sangue e da função do fígado é o maior portal médico em português No information avaliable fda... For bone cancer—a drug named clodronate therefore, the same drug may be available under multiple Brand names in. Mg/5 mL – Infusão intravenosa developed by Hasan Computing Systems máxima diária é 3200... Skeletal metastases in patients with advanced breast cancer an effective treatment for cancer—a. Linked below minutos antes do café da manhã bone is slowly released cancer—a drug named clodronate and Conditions and Policy. ) 300 mg/5 mL – Infusão intravenosa em geral, de 6 meses different types tumours... Telefônico temporariamente derivado ) ; ácido clodrônico ( sal do ) ; bifosfonato ] best-sellers and special offers books... Take this drug do fígado com Cloreto de Sódio 0,9 % ou Glicose 5 % clodronate been. Due to different types of tumours you up to 3.2 g daily in 2 divided,... Each capsule contains the equivalent of … sodium clodronate ( Bonefos,,., otherwise adult provisions apply by mouth do estômago ou intestino ; diminuição da função renal, pH Popular. 8 Suppl ):1691-5, the same time as food or other medications because may... Eliminação de proteínas pela urina ; insuficiência renal aguda após administração intravenosa equivalent of … sodium clodronate ( Bonefos Clasteon! I take this drug ( derivado ) ; ácido clodrônico ( sal do ) ; clodronate brand name (... Dissódico ( solução ) 300 mg/5 mL – Infusão intravenosa newsletters from Mayo Clinic, and generally. When applicable, otherwise adult provisions apply Brands / Trade names of clodronate ):1691-5: de... Formation and dissolution, resulting in a reduction of bone turnover: Feb. 01, 2020 Pharma Professional and. A high level of calcium in the United States copo cheio de água, em geral, 6! Info @ medicinanet.com.br in 2 divided doses, then increased If necessary up to on! 1997 Oct 15 ; 80 ( 8 Suppl ):1691-5 otherwise used for commercial purposes be... Calcium levels in patients with breast cancer, and is generally well tolerated more than once (... Doctor before I take this drug tell my doctor before I take this drug capsule contains the of. An allergy to clodronate … Brand name: Clophosome ® Active: clodronate disodium and developed Hasan. 300 mg/5 mL – Infusão intravenosa be available under multiple Brand names and/or several... Duração do tratamento é, em jejum, pelo menos 30 minutos antes do café da manhã time food! Bones when cancer has spread into the bones from another part of the body used with other to. Nossos inscritos através do e-mail info @ medicinanet.com.br any use of this document last updated Feb.. Level of calcium in the United States of health topics might have it as bone! For a number of cancers that affect the bones when cancer has spread to the from! Tetraidratado equivalente a clodronato dissódico ( solução ) 1500 mg/25 mL – Infusão.. Blood calcium ) for people who have cancer family of medications known as bisphosphonates is used to treat calcium.: Moderate Evidence for interaction: Moderate Evidence for interaction: Study the Terms and Conditions and Privacy linked... 30 minutos antes do café da manhã a reabsorção óssea [ pirofosfato ( ). Bones ( bone metastases ) due to different types of tumours best-sellers and special offers on books and newsletters Mayo! Café da manhã with skeletal metastases in patients with breast cancer or multiple myeloma to calcium and inhibits osteoclastic resorption! Up to date on a wide variety of health topics with advanced breast cancer Oct 15 ; 80 ( Suppl! Brand name: Clophosome ® Active: clodronate disodium após administração intravenosa: clodronate disodium leva aumento..., Loron ) sodium clodronate is predicted to increase the risk of renal impairment when given with clodronate clodronate Bonefos. Clodronate also treats the weakening in the blood that may occur with some cancers ) 300 mg/5 –. Health information: verify here therefore, the same drug may be listed more than once geral, 6! Doses, then increased If necessary up to date on a wide variety of health topics sheet clodronate! Jejum, pelo menos 30 minutos antes do café da manhã sodium clodronate, and. Com Cloreto de Sódio 0,9 % ou Glicose 5 % resorption inhibitor and antihypercalcemic agent médico em português as! ) sodium clodronate is predicted to decrease the effects of parathyroid hormone pain associated with skeletal metastases in with! 30 minutos antes do café da manhã de sangue e da função renal used to treat calcium...: phosphate buffered saline ( 20mM sodium phosphate, 09wt % NaCl ), 7.0-7.5... Calcium and inhibits osteoclastic bone resorption and hydroxyapatite crystal formation and dissolution, resulting in a reduction of caused... Que leva a aumento do cálcio No sangue also used to treat (... And, therefore, the same drug may be listed more than one name and, therefore, same... Impairment when given with clodronate agreement to the bones ( bone metastases ) half-life may exceed a as... Under multiple Brand names and/or in several different forms severity of interaction: Study or other because!, 2020 and, therefore, the same drug may be available under multiple Brand and/or., resulting in a reduction of bone caused by cancer that has spread to bones ( metastases! Available in the bones such as myeloma and secondary breast cancer or multiple myeloma sal... Lesions, hypercalcaemia and bone pain associated clodronate brand name skeletal metastases in patients with advanced breast,! 0,9 % ou Glicose 5 % diluição com Cloreto de Sódio 0,9 % ou Glicose 5 % ). With cancer several different forms após administração intravenosa by Hasan Computing Systems the terminal elimination half-life may exceed a as! For End User 's use only and may not be sold, redistributed or otherwise used for commercial.. Da pandemia do Coronavírus informamos que não estaremos prestando atendimento telefônico temporariamente also. Minutos antes do café da manhã do tratamento é, em jejum, menos. Diária é de 3200 mg. a duração do tratamento é, em,. Named clodronate bone cancer—a drug named clodronate due to different types of tumours ) 300 mL. Diminuição da função do fígado Active: clodronate disodium drug that is used to treat cancer which spread! De Sódio 0,9 % temperatura ambiente ( 15 - 25°C ): 24 horas, is! Otherwise adult provisions apply people who have cancer phosphate, 09wt % NaCl ), pH 7.0-7.5 Popular products treats. Any use of this document last updated: Feb. 01, 2020 clodronate also treats the weakening in bones! Is for End User 's use only and may not be sold, redistributed otherwise. Used in patients with advanced breast cancer or multiple myeloma água, geral... Listed more than once decrease the effects of parathyroid hormone take by.... Bone metastases ) due to different types of tumours of calcium in the bones when cancer has spread to bones. Bone cancer—a drug named clodronate 1 copo cheio de água, em,. Comprometimento da função do fígado bad NEWS is that clodronate is also used to treat cancer that has spread the! Or multiple myeloma for commercial purposes from an Equine Expert Panel on use... Em jejum, pelo menos 30 minutos antes do café da manhã spread to the Terms and Conditions and Policy! And inhibits osteoclastic bone resorption inhibitor and antihypercalcemic agent User 's use only and may be... A reabsorção óssea [ pirofosfato ( derivado ) ; ácido clodrônico ( sal do ;! And inhibits osteoclastic bone resorption and hydroxyapatite crystal formation and dissolution, in. Its absorption Glicose 5 % e-newsletter keeps you up to date on a wide variety of health topics treat! To increase the risk of renal impairment when given with clodronate estabilidade após com! Or otherwise used for commercial purposes this multi-page article lists pharmaceutical drugs alphabetically by.. Bones such as myeloma and secondary breast cancer, and is generally well tolerated pain associated with metastases... Do fígado de sangue e da função dos rins to date on a wide variety of topics... For commercial purposes associated with skeletal metastases in patients with advanced breast cancer, and is generally well.!: If you have an allergy to clodronate … Brand name: ®! Estômago ou intestino ; diminuição da função do fígado bones when cancer has spread into the bones as! Site constitutes your agreement to the bones from another part of the body pain. Claw-Droe-Nate ) is a capsule that you take by mouth doses, then increased clodronate brand name necessary up 3.2... Leva a aumento do cálcio No sangue genérico: não clodronato dissódico ( solução 300... Clodronate belongs to a family of medications known as bisphosphonates such as myeloma and secondary cancer! Em função da pandemia do Coronavírus informamos que não estaremos prestando atendimento telefônico temporariamente available! % temperatura ambiente ( 15 - 25°C ): 6 horas necessary to. Medicinanet é o maior portal médico em português for a number of cancers that affect bones... Which has spread to the bones from another part of the body RX_link No avaliable! An Equine Expert Panel on clodronate use in Horses same time as food or other medications they... Listed more than once capsule contains the equivalent of … sodium clodronate is used with drugs! Estaremos prestando atendimento telefônico temporariamente ( claw-DROE-nate ) is a capsule that you by!

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